|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0019704,
umls-concept:C0026882,
umls-concept:C0030705,
umls-concept:C0033105,
umls-concept:C0035648,
umls-concept:C0040808,
umls-concept:C0132326,
umls-concept:C0164662,
umls-concept:C0205195,
umls-concept:C0205265,
umls-concept:C0209738,
umls-concept:C1555582
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2008-3-17
|
|
pubmed:abstractText |
A fixed-dose combination of stavudine, lamivudine, and nevirapine (d4T/3TC/NVP) is extensively used as initial antiretroviral regimen in developing countries. K65R mutations that occur after failing this regimen prevent the use of tenofovir, didanosine, and abcavir in the second-line regimen.
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1386-6532
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
41
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
310-3
|
|
pubmed:meshHeading |
pubmed-meshheading:18316243-Adult,
pubmed-meshheading:18316243-Amino Acid Substitution,
pubmed-meshheading:18316243-Anti-HIV Agents,
pubmed-meshheading:18316243-CD4 Lymphocyte Count,
pubmed-meshheading:18316243-Drug Resistance, Viral,
pubmed-meshheading:18316243-Female,
pubmed-meshheading:18316243-HIV Infections,
pubmed-meshheading:18316243-HIV-1,
pubmed-meshheading:18316243-Humans,
pubmed-meshheading:18316243-Lamivudine,
pubmed-meshheading:18316243-Male,
pubmed-meshheading:18316243-Mutation, Missense,
pubmed-meshheading:18316243-Nevirapine,
pubmed-meshheading:18316243-Prevalence,
pubmed-meshheading:18316243-RNA, Viral,
pubmed-meshheading:18316243-Risk Factors,
pubmed-meshheading:18316243-Stavudine,
pubmed-meshheading:18316243-Viral Load
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Prevalence and risk factors for developing K65R mutations among HIV-1 infected patients who fail an initial regimen of fixed-dose combination of stavudine, lamivudine, and nevirapine.
|
|
pubmed:affiliation |
Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok 10400, Thailand. rasuy@mahidol.ac.th
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
