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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1977-9-22
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pubmed:abstractText |
A new case of glucosephosphate isomerase deficiency in a Belgian family is described. The activity of the enzyme was decreased to about 25-30% of the normal value. Characterization of the defect enzyme showed a decreased thermostability. Heating of the enzyme at 45 degrees C showed a loss of activity of 50% after 90 min. The pH-optimum and the KM-value for fructose 6-phosphate were normal. The electrophoretic pattern showed a faster migration. The variant described here differs from all known variants. Therefore we propose to give to this new variant the name GPI-Kortrijk.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
121-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18297-Anemia, Hemolytic, Congenital Nonspherocytic,
pubmed-meshheading:18297-Blood Platelets,
pubmed-meshheading:18297-Blood Protein Electrophoresis,
pubmed-meshheading:18297-Child,
pubmed-meshheading:18297-Electrophoresis, Starch Gel,
pubmed-meshheading:18297-Erythrocytes,
pubmed-meshheading:18297-Female,
pubmed-meshheading:18297-Genotype,
pubmed-meshheading:18297-Glucose-6-Phosphate Isomerase,
pubmed-meshheading:18297-Glycolysis,
pubmed-meshheading:18297-Hot Temperature,
pubmed-meshheading:18297-Humans,
pubmed-meshheading:18297-Hydrogen-Ion Concentration,
pubmed-meshheading:18297-Kinetics,
pubmed-meshheading:18297-Leukocytes,
pubmed-meshheading:18297-Male
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pubmed:year |
1977
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pubmed:articleTitle |
A new variant of glucosephosphate isomerase deficiency: GPI-Kortrijk.
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pubmed:publicationType |
Journal Article,
Case Reports
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