rdf:type |
|
lifeskim:mentions |
umls-concept:C0021760,
umls-concept:C0032659,
umls-concept:C0035647,
umls-concept:C0153452,
umls-concept:C0422792,
umls-concept:C0678951,
umls-concept:C0812246,
umls-concept:C1413745,
umls-concept:C1456820,
umls-concept:C1522669,
umls-concept:C1709269
|
pubmed:issue |
4
|
pubmed:dateCreated |
2008-2-11
|
pubmed:abstractText |
Gallbladder carcinoma (GBC) is highly aggressive neoplasm which arises in the background of gall stones and inflammation. GBC affects women 2-3 times more frequently than men. Pro-inflammatory TNFA and IL6 gene polymorphism has been associated with various inflammatory diseases. The aim of this study was to investigate whether TNFA -308 (G/A) and IL6 -174 G/C polymorphisms within flanking region of the genes are associated with GBC susceptibility.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1513-7368
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
567-72
|
pubmed:meshHeading |
pubmed-meshheading:18260730-Case-Control Studies,
pubmed-meshheading:18260730-Female,
pubmed-meshheading:18260730-Gallbladder Neoplasms,
pubmed-meshheading:18260730-Genetic Predisposition to Disease,
pubmed-meshheading:18260730-Genotype,
pubmed-meshheading:18260730-Humans,
pubmed-meshheading:18260730-India,
pubmed-meshheading:18260730-Interleukin-6,
pubmed-meshheading:18260730-Male,
pubmed-meshheading:18260730-Middle Aged,
pubmed-meshheading:18260730-Polymerase Chain Reaction,
pubmed-meshheading:18260730-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:18260730-Polymorphism, Single Nucleotide,
pubmed-meshheading:18260730-Risk Factors,
pubmed-meshheading:18260730-Tumor Necrosis Factor-alpha
|
pubmed:articleTitle |
Do TNFA -308 G/A and IL6 -174 G/C gene polymorphisms modulate risk of gallbladder cancer in the north Indian population?
|
pubmed:affiliation |
Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medica Sciences, Lucknow, India.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|