|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0040300,
umls-concept:C0185117,
umls-concept:C0205234,
umls-concept:C0215848,
umls-concept:C0242184,
umls-concept:C0279328,
umls-concept:C0392756,
umls-concept:C0917798,
umls-concept:C2003941,
umls-concept:C2911684
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2008-2-26
|
|
pubmed:abstractText |
The usefulness of hyperbaric oxygen (HBO) and normobaric hyperoxia in acute ischemic stroke is being reexplored because both improve outcome in experimental cerebral ischemia. However, even the basic mechanisms underlying oxygen therapy are poorly understood. We investigated the effect of both oxygen therapies on tissue hypoxia and on the transcription factor hypoxia-inducible factor-1 alpha.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-(2-nitro-1H-imidazol-1-yl)-N-(2,2...,
http://linkedlifedata.com/resource/pubmed/chemical/Etanidazole,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrocarbons, Fluorinated,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1,
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1524-4628
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
39
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1000-6
|
|
pubmed:meshHeading |
pubmed-meshheading:18239183-Animals,
pubmed-meshheading:18239183-Brain,
pubmed-meshheading:18239183-Brain Ischemia,
pubmed-meshheading:18239183-Cerebral Cortex,
pubmed-meshheading:18239183-Corpus Striatum,
pubmed-meshheading:18239183-Down-Regulation,
pubmed-meshheading:18239183-Etanidazole,
pubmed-meshheading:18239183-Fluorescent Antibody Technique,
pubmed-meshheading:18239183-Hydrocarbons, Fluorinated,
pubmed-meshheading:18239183-Hyperbaric Oxygenation,
pubmed-meshheading:18239183-Hypoxia, Brain,
pubmed-meshheading:18239183-Hypoxia-Inducible Factor 1,
pubmed-meshheading:18239183-Indicators and Reagents,
pubmed-meshheading:18239183-Infarction, Middle Cerebral Artery,
pubmed-meshheading:18239183-Male,
pubmed-meshheading:18239183-Mice,
pubmed-meshheading:18239183-Mice, Inbred C57BL,
pubmed-meshheading:18239183-Oxygen,
pubmed-meshheading:18239183-Oxygen Consumption,
pubmed-meshheading:18239183-RNA, Messenger,
pubmed-meshheading:18239183-Staining and Labeling,
pubmed-meshheading:18239183-Vascular Endothelial Growth Factor A
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Hyperbaric oxygen reduces tissue hypoxia and hypoxia-inducible factor-1 alpha expression in focal cerebral ischemia.
|
|
pubmed:affiliation |
Department of Neurology, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
