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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-1-28
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pubmed:abstractText |
Proteomic profiling using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF MS) enables the identification of biomarkers for cancer. We evaluated the sensitivity and specificity of SELDI-TOF MS for detection of established hepatocellular cancer (HCC) and compared it against alpha-fetoprotein (AFP), Lens culinaris agglutinin-reactive AFP (AFP-L3), and prothrombin induced by vitamin K absence-II (PIVKA-II).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AfdhalNezam HNH,
pubmed-author:AsaraJohn MJM,
pubmed-author:BhaskarKillimangalamK,
pubmed-author:GrallFranckF,
pubmed-author:GuerreroManuelM,
pubmed-author:KalmowitzBrettB,
pubmed-author:LibermannTowia ATA,
pubmed-author:OtuHasan HHH,
pubmed-author:SpentzosDimitriosD,
pubmed-author:WellsMeghanM,
pubmed-author:ZinkinNoah TNT
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
470-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18223221-Adult,
pubmed-meshheading:18223221-Aged,
pubmed-meshheading:18223221-Aged, 80 and over,
pubmed-meshheading:18223221-Carcinoma, Hepatocellular,
pubmed-meshheading:18223221-Cystatin C,
pubmed-meshheading:18223221-Cystatins,
pubmed-meshheading:18223221-Female,
pubmed-meshheading:18223221-Hepatitis C, Chronic,
pubmed-meshheading:18223221-Humans,
pubmed-meshheading:18223221-Liver Cirrhosis,
pubmed-meshheading:18223221-Liver Neoplasms,
pubmed-meshheading:18223221-Male,
pubmed-meshheading:18223221-Middle Aged,
pubmed-meshheading:18223221-Multivariate Analysis,
pubmed-meshheading:18223221-Proteomics,
pubmed-meshheading:18223221-Sensitivity and Specificity,
pubmed-meshheading:18223221-Spectrometry, Mass, Matrix-Assisted Laser...,
pubmed-meshheading:18223221-Tumor Markers, Biological,
pubmed-meshheading:18223221-alpha-Fetoproteins
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pubmed:year |
2008
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pubmed:articleTitle |
Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease.
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pubmed:affiliation |
Liver Center, Department of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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