Linked Life Data

1818326

Source:http://linkedlifedata.com/resource/pubmed/id/1818326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1992-7-13
pubmed:abstractText
The analgesic action of D-phenylalanine (D-Phe) is well known. It has been demonstrated in hot-plate tests on mice that combining D-Phe with narcotic analgesics already with doses inactive on separate application. In combination with D-Phe, a dose of morphine less by half compared to its unique use does not reduce analgesic activity in rats, but after six weeks of treatment some undesirable side effects like dependence, behavioural disorders and growth retardation are markedly lowered. These results suggest the possibility to design a combined drug similarly effective as well-introduced narcotic analgesics, but better tolerated.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
875-7
pubmed:dateRevised
2007-1-29
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[The analgesic action of d-phenylalanine in combination with morphine or methadone].
pubmed:affiliation
Pharmakologische Forschungsgemeinschaft Biopharm GmbH, Berlin.
pubmed:publicationType
Journal Article, English Abstract