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rdf:type |
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lifeskim:mentions |
umls-concept:C0007301,
umls-concept:C0007303,
umls-concept:C0017262,
umls-concept:C0020564,
umls-concept:C0035647,
umls-concept:C0039099,
umls-concept:C0083867,
umls-concept:C0185117,
umls-concept:C0253373,
umls-concept:C0263680,
umls-concept:C0591833,
umls-concept:C0699900,
umls-concept:C0851285,
umls-concept:C1550315,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-21
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pubmed:abstractText |
To examine whether the endogenous expression of growth differentiation factor 5 (GDF-5) and bone morphogenetic protein 7 (BMP-7) is altered in the cartilage and synovium of human tumor necrosis factor alpha (TNFalpha)-transgenic (hTNFtg) mice with chronic arthritis, and to investigate the response of hTNFtg chondrocytes as well as fibroblast-like synoviocytes (FLS) to these morphogens in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
109-18
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18163510-Animals,
pubmed-meshheading:18163510-Arthritis,
pubmed-meshheading:18163510-Bone Morphogenetic Protein 7,
pubmed-meshheading:18163510-Bone Morphogenetic Proteins,
pubmed-meshheading:18163510-Cartilage, Articular,
pubmed-meshheading:18163510-Cell Division,
pubmed-meshheading:18163510-Cells, Cultured,
pubmed-meshheading:18163510-Chondrocytes,
pubmed-meshheading:18163510-Chronic Disease,
pubmed-meshheading:18163510-Extracellular Matrix,
pubmed-meshheading:18163510-Gene Expression,
pubmed-meshheading:18163510-Growth Differentiation Factor 5,
pubmed-meshheading:18163510-Hypertrophy,
pubmed-meshheading:18163510-Mice,
pubmed-meshheading:18163510-Mice, Inbred C57BL,
pubmed-meshheading:18163510-Mice, Transgenic,
pubmed-meshheading:18163510-Synovial Membrane,
pubmed-meshheading:18163510-Transforming Growth Factor beta
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pubmed:year |
2008
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pubmed:articleTitle |
Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: potential importance for cartilage breakdown and synovial hypertrophy.
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pubmed:affiliation |
University of Vienna, Vienna, Austria. klaus.bobacz@meduniwien.ac.at
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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