Source:http://linkedlifedata.com/resource/pubmed/id/18054566
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2007-12-6
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| pubmed:abstractText |
SRF (Serum Response Factor), a widely expressed transcription factor, controls expression of mitogen-responsive and muscle-specific genes, thereby regulating the contractile actin microfilament. Genetic Srf deletion studies showed SRF to be indispensable for in vivo skeletal and cardiac muscle cell development. We now investigated for the first time in vivo SRF functions in smooth muscle cells of adult mice.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
1528-0012
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
133
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1948-59
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| pubmed:meshHeading |
pubmed-meshheading:18054566-Animals,
pubmed-meshheading:18054566-Cells, Cultured,
pubmed-meshheading:18054566-Disease Models, Animal,
pubmed-meshheading:18054566-Gastrointestinal Tract,
pubmed-meshheading:18054566-Intestinal Obstruction,
pubmed-meshheading:18054566-Mice,
pubmed-meshheading:18054566-Myocytes, Smooth Muscle,
pubmed-meshheading:18054566-Serum Response Factor
|
| pubmed:year |
2007
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| pubmed:articleTitle |
Severe intestinal obstruction on induced smooth muscle-specific ablation of the transcription factor SRF in adult mice.
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| pubmed:affiliation |
Interfaculty Institute for Cell Biology, Tuebingen University, Tuebingen, Germany.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|