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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-18
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pubmed:abstractText |
In the present study, we examined whether differences in the severity of sepsis translate to differences in the pharmacokinetic profile of linezolid in plasma and the interstitium of target tissues after a single intravenous dose of 600 mg by means of the microdialysis technique.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1460-2091
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-6
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pubmed:meshHeading |
pubmed-meshheading:17999976-Acetamides,
pubmed-meshheading:17999976-Adipose Tissue,
pubmed-meshheading:17999976-Administration, Oral,
pubmed-meshheading:17999976-Anti-Bacterial Agents,
pubmed-meshheading:17999976-Chromatography, High Pressure Liquid,
pubmed-meshheading:17999976-Dose-Response Relationship, Drug,
pubmed-meshheading:17999976-Humans,
pubmed-meshheading:17999976-Injections, Intravenous,
pubmed-meshheading:17999976-Microdialysis,
pubmed-meshheading:17999976-Muscle, Skeletal,
pubmed-meshheading:17999976-Oxazolidinones,
pubmed-meshheading:17999976-Sepsis,
pubmed-meshheading:17999976-Severity of Illness Index,
pubmed-meshheading:17999976-Tissue Distribution
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pubmed:year |
2008
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pubmed:articleTitle |
Effect of severity of sepsis on tissue concentrations of linezolid.
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pubmed:affiliation |
Department of Clinical Pharmacology, Division of Clinical Pharmacokinetics, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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