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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20
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pubmed:dateCreated |
2007-10-19
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pubmed:abstractText |
Treatment of malignant glioma involves concomitant temozolomide and ionizing radiation (IR). Nevertheless, overall patient survival remains poor. This study was designed to evaluate if addition of Ad.Egr-tumor necrosis factor (TNF), a replication defective adenovector encoding a cDNA for TNF-alpha, to temozolomide and IR can improve overall antiglioma effect.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6217-23
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pubmed:meshHeading |
pubmed-meshheading:17947489-Adenoviridae,
pubmed-meshheading:17947489-Animals,
pubmed-meshheading:17947489-Antineoplastic Agents, Alkylating,
pubmed-meshheading:17947489-Brain Neoplasms,
pubmed-meshheading:17947489-Cell Line, Tumor,
pubmed-meshheading:17947489-Combined Modality Therapy,
pubmed-meshheading:17947489-DNA, Complementary,
pubmed-meshheading:17947489-Dacarbazine,
pubmed-meshheading:17947489-Female,
pubmed-meshheading:17947489-Gene Therapy,
pubmed-meshheading:17947489-Gene Transfer Techniques,
pubmed-meshheading:17947489-Glioma,
pubmed-meshheading:17947489-Humans,
pubmed-meshheading:17947489-Mice,
pubmed-meshheading:17947489-Mice, Nude,
pubmed-meshheading:17947489-Neoplasm Transplantation,
pubmed-meshheading:17947489-Time Factors,
pubmed-meshheading:17947489-Treatment Outcome,
pubmed-meshheading:17947489-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
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pubmed:affiliation |
Section of Neurosurgery, Department of Surgery, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois 60637, USA. byamini@surgery.bsd.uchicago.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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