17933841

Source:http://linkedlifedata.com/resource/pubmed/id/17933841

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0014597, umls-concept:C0022646, umls-concept:C0022677, umls-concept:C0023693, umls-concept:C0026764, umls-concept:C0086418, umls-concept:C0205263, umls-concept:C1523298, umls-concept:C1524075
pubmed:issue	3
pubmed:dateCreated	2008-2-26
pubmed:abstractText	To determine the role of epithelial-mesenchymal transition (EMT) as a potential mechanism contributing to the characteristic tubulointerstitial renal fibrosis in multiple myeloma, we examined whether myeloma light chains (LCs) directly induce EMT in human renal proximal tubule epithelial cells (PTECs).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8706402
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/BMP7 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Protein 7, http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Proteins, http://linkedlifedata.com/resource/pubmed/chemical/CCL2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cadherins, http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2, http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins, http://linkedlifedata.com/resource/pubmed/chemical/FSP1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Light Chains, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6, http://linkedlifedata.com/resource/pubmed/chemical/Pituitary Adenylate..., http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta1, http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	1460-2385
pubmed:author	pubmed-author:BatumanVecihiV, pubmed-author:Hering-SmithKathleen SKS, pubmed-author:KoçLL, pubmed-author:SimonEric EEE
pubmed:issnType	Electronic
pubmed:volume	23
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	860-70
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17933841-Bone Morphogenetic Protein 7, pubmed-meshheading:17933841-Bone Morphogenetic Proteins, pubmed-meshheading:17933841-Cadherins, pubmed-meshheading:17933841-Calcium-Binding Proteins, pubmed-meshheading:17933841-Cell Aggregation, pubmed-meshheading:17933841-Cell Transdifferentiation, pubmed-meshheading:17933841-Cells, Cultured, pubmed-meshheading:17933841-Chemokine CCL2, pubmed-meshheading:17933841-Epithelial Cells, pubmed-meshheading:17933841-Extracellular Matrix Proteins, pubmed-meshheading:17933841-Fibrosis, pubmed-meshheading:17933841-Humans, pubmed-meshheading:17933841-Immunoglobulin Light Chains, pubmed-meshheading:17933841-Interleukin-6, pubmed-meshheading:17933841-Kidney Tubules, Proximal, pubmed-meshheading:17933841-Mesoderm, pubmed-meshheading:17933841-Multiple Myeloma, pubmed-meshheading:17933841-Pituitary Adenylate Cyclase-Activating Polypeptide, pubmed-meshheading:17933841-Transforming Growth Factor beta, pubmed-meshheading:17933841-Transforming Growth Factor beta1, pubmed-meshheading:17933841-p38 Mitogen-Activated Protein Kinases
pubmed:year	2008
pubmed:articleTitle	Myeloma light chains induce epithelial-mesenchymal transition in human renal proximal tubule epithelial cells.
pubmed:affiliation	Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't