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rdf:type |
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lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0086418,
umls-concept:C0087071,
umls-concept:C0127082,
umls-concept:C0185117,
umls-concept:C1280500,
umls-concept:C1367342,
umls-concept:C1533691,
umls-concept:C2003787,
umls-concept:C2911684
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pubmed:issue |
9
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pubmed:dateCreated |
2007-10-22
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pubmed:abstractText |
The traditional Chinese medication Shugansanjie Tang (SGT), whose active component is Akebia Trifoliate Koidz, possesses potential anti-tumor and immunostimulatory effects especially for breast cancer. The invasive processes of such cancers have been attributed to matrix metalloproteinases (MMPs) which may be the key factor mediating this process. Telomerase reverse transcriptase (TERT) catalyze the lengthening of telomeres, which prolongs cell life and interrupts natural cell death. The aim of this study is to determine the effects of Shugansanjie Tang on MMP levels and TERT activity using breast cancer cell lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-(4-iodophenyl)-3-(4-nitrophenyl)-5...,
http://linkedlifedata.com/resource/pubmed/chemical/Drugs, Chinese Herbal,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases,
http://linkedlifedata.com/resource/pubmed/chemical/Protease Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Telomerase,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazolium Salts
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0753-3322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-5
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pubmed:meshHeading |
pubmed-meshheading:17913446-Apoptosis,
pubmed-meshheading:17913446-Breast Neoplasms,
pubmed-meshheading:17913446-Cell Line, Tumor,
pubmed-meshheading:17913446-Cell Proliferation,
pubmed-meshheading:17913446-Drugs, Chinese Herbal,
pubmed-meshheading:17913446-Female,
pubmed-meshheading:17913446-Humans,
pubmed-meshheading:17913446-Immunohistochemistry,
pubmed-meshheading:17913446-In Situ Nick-End Labeling,
pubmed-meshheading:17913446-Matrix Metalloproteinase 1,
pubmed-meshheading:17913446-Matrix Metalloproteinase 3,
pubmed-meshheading:17913446-Matrix Metalloproteinase 9,
pubmed-meshheading:17913446-Matrix Metalloproteinases,
pubmed-meshheading:17913446-Protease Inhibitors,
pubmed-meshheading:17913446-RNA, Messenger,
pubmed-meshheading:17913446-RNA, Neoplasm,
pubmed-meshheading:17913446-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17913446-Telomerase,
pubmed-meshheading:17913446-Tetrazolium Salts
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pubmed:year |
2007
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pubmed:articleTitle |
Effects of Shugansanjie Tang on matrix metalloproteinases 1, 3 and 9 and telomerase reverse transcriptase expression in human breast cells in vitro.
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pubmed:affiliation |
UNIMED Medical Institute, Hong Kong, PR China.
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pubmed:publicationType |
Journal Article
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