Source:http://linkedlifedata.com/resource/pubmed/id/17804466
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2007-12-17
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pubmed:abstractText |
Extracellular matrix degradation, mediated by the urokinase plasminogen activation (uPA) system, is a critical step in tumor invasion and metastasis. High tumor levels of uPA and its inhibitor PAI-1 have been correlated with poor cancer prognosis. We examined four single nucleotide polymorphisms (SNPs) with a potential effect on expression of genes in the uPA system for their role in colorectal cancer susceptibility and prognosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1569-8041
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1990-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17804466-Case-Control Studies,
pubmed-meshheading:17804466-Cohort Studies,
pubmed-meshheading:17804466-Colorectal Neoplasms,
pubmed-meshheading:17804466-Female,
pubmed-meshheading:17804466-Genetic Predisposition to Disease,
pubmed-meshheading:17804466-Humans,
pubmed-meshheading:17804466-Male,
pubmed-meshheading:17804466-Polymorphism, Single Nucleotide,
pubmed-meshheading:17804466-Survival Analysis,
pubmed-meshheading:17804466-Sweden,
pubmed-meshheading:17804466-Urokinase-Type Plasminogen Activator
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pubmed:year |
2007
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pubmed:articleTitle |
Polymorphisms in the genes of the urokinase plasminogen activation system in relation to colorectal cancer.
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pubmed:affiliation |
Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany. a.foersti@dkfz.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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