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rdf:type |
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lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0017638,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0085862,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0279024,
umls-concept:C0387583,
umls-concept:C0851827,
umls-concept:C1257954,
umls-concept:C1299583,
umls-concept:C1519249,
umls-concept:C1549571,
umls-concept:C1565860,
umls-concept:C1608386,
umls-concept:C1701901,
umls-concept:C1705323,
umls-concept:C2911684
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pubmed:issue |
10
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pubmed:dateCreated |
2007-8-30
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pubmed:abstractText |
Patients with a malignant glioma have a very poor prognosis. Cyclooxygenase-2 (COX-2) protein is regularly upregulated in gliomas and might be a potential therapeutic target. The effects of three selective COX-2 inhibitors were studied on three human glioma cell lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2 Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/N-(2-cyclohexyloxy-4-nitrophenyl)met...,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrobenzenes,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Radiation-Protective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazines,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/celecoxib,
http://linkedlifedata.com/resource/pubmed/chemical/meloxicam
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0955-3002
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
677-85
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pubmed:meshHeading |
pubmed-meshheading:17729162-Cell Line, Tumor,
pubmed-meshheading:17729162-Cell Proliferation,
pubmed-meshheading:17729162-Cyclooxygenase 2,
pubmed-meshheading:17729162-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:17729162-Dose-Response Relationship, Radiation,
pubmed-meshheading:17729162-Flow Cytometry,
pubmed-meshheading:17729162-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17729162-Glioma,
pubmed-meshheading:17729162-Humans,
pubmed-meshheading:17729162-Neoplasms,
pubmed-meshheading:17729162-Nitrobenzenes,
pubmed-meshheading:17729162-Pyrazoles,
pubmed-meshheading:17729162-Radiation-Protective Agents,
pubmed-meshheading:17729162-Sulfonamides,
pubmed-meshheading:17729162-Thiazines,
pubmed-meshheading:17729162-Thiazoles
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pubmed:year |
2007
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pubmed:articleTitle |
Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration.
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pubmed:affiliation |
Department of Radiation Oncology, division Radiobiology, VU University Medical Center, Amsterdam, The Netherlands. gk.kuipers@vumc.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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