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pubmed-article:17727850pubmed:abstractTextThe promoter of P receptor isoform B (PR-B) has recently been shown to be hypermethylated in endometriotic tissues, but one question remains as what causes the aberrant methylation. We show that sustained stimulation of an epithelial-like endometriotic cell line with tumor necrosis factor alpha stimulation for 30 days induced partial methylation in the promoter region of PR-B with concomitant reduction of PR-B expression.lld:pubmed
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pubmed-article:17727850pubmed:articleTitleProlonged stimulation with tumor necrosis factor-alpha induced partial methylation at PR-B promoter in immortalized epithelial-like endometriotic cells.lld:pubmed
pubmed-article:17727850pubmed:affiliationDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.lld:pubmed
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