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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-7-1
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pubmed:abstractText |
The promoter of P receptor isoform B (PR-B) has recently been shown to be hypermethylated in endometriotic tissues, but one question remains as what causes the aberrant methylation. We show that sustained stimulation of an epithelial-like endometriotic cell line with tumor necrosis factor alpha stimulation for 30 days induced partial methylation in the promoter region of PR-B with concomitant reduction of PR-B expression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1556-5653
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
234-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17727850-Cell Line,
pubmed-meshheading:17727850-DNA Methylation,
pubmed-meshheading:17727850-Down-Regulation,
pubmed-meshheading:17727850-Endometriosis,
pubmed-meshheading:17727850-Endometrium,
pubmed-meshheading:17727850-Epithelial Cells,
pubmed-meshheading:17727850-Female,
pubmed-meshheading:17727850-Humans,
pubmed-meshheading:17727850-Promoter Regions, Genetic,
pubmed-meshheading:17727850-Receptors, Progesterone,
pubmed-meshheading:17727850-Stromal Cells,
pubmed-meshheading:17727850-Time Factors,
pubmed-meshheading:17727850-Tumor Necrosis Factor-alpha
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pubmed:year |
2008
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pubmed:articleTitle |
Prolonged stimulation with tumor necrosis factor-alpha induced partial methylation at PR-B promoter in immortalized epithelial-like endometriotic cells.
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pubmed:affiliation |
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
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pubmed:publicationType |
Journal Article
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