Linked Life Data

17712295

Source:http://linkedlifedata.com/resource/pubmed/id/17712295

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-8-22
pubmed:abstractText
In the present paper, we describe the results of a prospective trial that compared isocenter shifts produced by BAT Ultrasound (Nomos, Sewicky, PA) to those produced by a computed tomography (CT) unit in the treatment room to aid in positioning during image-guided radiation therapy. The trial included 15 consecutive patients with localized prostate cancer. All patients underwent CT and MR simulation immobilized supine in an Alpha Cradle and were treated with intensity-modulated radiation therapy. BAT Ultrasound was used daily to correct for interfraction motion by obtaining shift in the x, y, and z directions. Two days per week during therapy, CT scans blinded to the ultrasound shifts were obtained and recorded. We analyzed 218 alignments from the 15 patients and observed a high level of correlation between the CT and ultrasound isocenter shifts (correlation coefficients: 0.877 anterior-posterior, 0.842 lateral, and 0.831 superior-inferior). The systematic differences were less than 1 mm, and the random differences were approximately 2 mm. The average absolute differences, including both systemic and random differences, were less than 2 mm in all directions. The isocenter shifts generated by using a CT unit in the treatment room correlate highly with shifts produced by the BAT Ultrasound system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1526-9914
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2268
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Comparing computed tomography localization with daily ultrasound during image-guided radiation therapy for the treatment of prostate cancer: a prospective evaluation.
pubmed:affiliation
Fox Chase Cancer Center, Department of Radiation Oncology, Philadelphia, Pennsylvania 19111, USA. S_Feigenberg@FCCC.edu
pubmed:publicationType
Journal Article, Comparative Study, Controlled Clinical Trial