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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-9-25
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pubmed:abstractText |
Further optimization of dendritic cell (DC)-based vaccines is required clinically against advanced stage cancer. Given the broad range of expression levels observed in the recently defined tumor antigen EphA2 in a diverse types of cancers, especially in advanced stage or metastatic cancers, the authors evaluated the effectiveness of vaccination using DCs pulsed with EphA2-derived peptides (Eph-DCs) in a murine colon cancer model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1469-77
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17685394-Animals,
pubmed-meshheading:17685394-Blotting, Western,
pubmed-meshheading:17685394-CD8-Positive T-Lymphocytes,
pubmed-meshheading:17685394-Cancer Vaccines,
pubmed-meshheading:17685394-Carcinoma,
pubmed-meshheading:17685394-Colonic Neoplasms,
pubmed-meshheading:17685394-Dendritic Cells,
pubmed-meshheading:17685394-Disease Models, Animal,
pubmed-meshheading:17685394-Female,
pubmed-meshheading:17685394-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17685394-Interferon-gamma,
pubmed-meshheading:17685394-Mice,
pubmed-meshheading:17685394-Mice, Inbred C57BL,
pubmed-meshheading:17685394-Receptor, EphA2,
pubmed-meshheading:17685394-Time Factors,
pubmed-meshheading:17685394-Up-Regulation
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pubmed:year |
2007
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pubmed:articleTitle |
Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines.
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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