Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1992-2-25
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pubmed:abstractText |
The levels of interleukin 1 beta (IL-1 beta) and tumor necrosis factor (TNF) in peritoneal fluid (PF-IL-1 beta and PF-TNF) and production of IL-1 beta and TNF by peritoneal macrophages were determined in patients with benign gynecologic disease. The level of PF-IL-1 beta was elevated in the acute pelvic inflammatory disease (PID) and stages I and II endometriosis (E I/II) groups compared with the normal pelvis group, but not in the myoma of the uterus, ovarian cyst, and postinflammatory pelvic adhesion groups. The level of PF-TNF was elevated in the PID, EI/II and stages III and IV endometriosis (EIII/IV) groups. There was no correlation between the levels of PF-IL-1 beta and PF-TNF. Neither the level of PF-IL-1 beta nor that of PF-TNF was correlated with the concentration of peritoneal macrophages. Peritoneal macrophages produced IL-1 beta and TNF in vitro in the absence of stimulants. The levels of PF-IL-1 beta and PF-TNF are presumably linked to the activation of peritoneal macrophages.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
1046-7408
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
26
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
62-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1768319-Adult,
pubmed-meshheading:1768319-Ascitic Fluid,
pubmed-meshheading:1768319-Cell Count,
pubmed-meshheading:1768319-Chi-Square Distribution,
pubmed-meshheading:1768319-Female,
pubmed-meshheading:1768319-Genital Diseases, Female,
pubmed-meshheading:1768319-Humans,
pubmed-meshheading:1768319-Interleukin-1,
pubmed-meshheading:1768319-Macrophages,
pubmed-meshheading:1768319-Tumor Necrosis Factor-alpha
|
pubmed:year |
1991
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pubmed:articleTitle |
Peritoneal fluid interleukin-1 beta and tumor necrosis factor in patients with benign gynecologic disease.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro
|