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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2007-10-8
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pubmed:abstractText |
Alpha-methylacyl-CoA racemase (AMACR), which prepares branched chain fatty acids to be metabolized for energy and is implicated in the activation of the COX-inhibiting form of ibuprofen, is overexpressed in prostate cancer and its precursor lesions. Significant differences in AMACR allele frequencies have been reported for hereditary prostate cancer (HPC), but the relevance of AMACR in the context of its substrates have not been studied.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1487-97
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17680641-Aged,
pubmed-meshheading:17680641-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:17680641-Case-Control Studies,
pubmed-meshheading:17680641-Chemoprevention,
pubmed-meshheading:17680641-Genetic Markers,
pubmed-meshheading:17680641-Genetic Predisposition to Disease,
pubmed-meshheading:17680641-Genotype,
pubmed-meshheading:17680641-Humans,
pubmed-meshheading:17680641-Ibuprofen,
pubmed-meshheading:17680641-Logistic Models,
pubmed-meshheading:17680641-Male,
pubmed-meshheading:17680641-Middle Aged,
pubmed-meshheading:17680641-Polymorphism, Single Nucleotide,
pubmed-meshheading:17680641-Prostatic Neoplasms,
pubmed-meshheading:17680641-Racemases and Epimerases,
pubmed-meshheading:17680641-United States
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pubmed:year |
2007
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pubmed:articleTitle |
Polymorphic variants in alpha-methylacyl-CoA racemase and prostate cancer.
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pubmed:affiliation |
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA. daughers@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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