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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1992-2-14
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pubmed:abstractText |
A Mab set was used to study immunological phenotype of lymphocytes of five patients bearing stage IV malignant melanoma and its changes developing in the course of interleukin-2 (Euro cetus) immunotherapy. Patients were shown to have lowered counts of T cells (mainly due to T-helper/inducers), B cells and lymphocytes expressing adhesion and activation molecules as well as abnormal immunoregulatory cell ratio. Two patients receiving interleukin-2 achieved a response. Follow-up of antigen expression revealed a rise in natural killer and immunoregulatory T lymphocyte levels in the responders whereas activation antigens and B cell levels were increased in all the patients.
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pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0507-3758
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
37
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
544-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1767507-Antibodies, Monoclonal,
pubmed-meshheading:1767507-B-Lymphocytes,
pubmed-meshheading:1767507-Dacarbazine,
pubmed-meshheading:1767507-Drug Therapy, Combination,
pubmed-meshheading:1767507-Humans,
pubmed-meshheading:1767507-Immunophenotyping,
pubmed-meshheading:1767507-Interleukin-2,
pubmed-meshheading:1767507-Lymphocyte Activation,
pubmed-meshheading:1767507-Lymphocyte Subsets,
pubmed-meshheading:1767507-Lymphocytes,
pubmed-meshheading:1767507-Melanoma,
pubmed-meshheading:1767507-T-Lymphocytes
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pubmed:year |
1991
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pubmed:articleTitle |
[Immunophenotype of lymphocytes of patients with malignant melanoma and its dynamics during immunotherapy with interleukin-2].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|