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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-8-3
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pubmed:abstractText |
Small-molecule ligands specific for prostate-specific membrane antigen (PSMA) have the potential to improve prostate cancer imaging. However, highly charged ligands are difficult to label with 99mTc and to purify. In this study, we present an adamantane-trimerized small molecule that has nanomolar binding to PSMA and also has 12 negative charges.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-10101833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-11016653,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-11085533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-11752087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-12849974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-12920850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-12926236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-12940233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-14640766,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-15548077,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-15661684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-16285907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-17193697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-7511053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-8229241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-8417812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-9751609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17631555-9804043
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0161-5505
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1379-89
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:17631555-Antigens, Surface,
pubmed-meshheading:17631555-Cell Line, Tumor,
pubmed-meshheading:17631555-Glutamate Carboxypeptidase II,
pubmed-meshheading:17631555-Humans,
pubmed-meshheading:17631555-Isotope Labeling,
pubmed-meshheading:17631555-Male,
pubmed-meshheading:17631555-Sodium Pertechnetate Tc 99m,
pubmed-meshheading:17631555-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
2007
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pubmed:articleTitle |
Production of multimeric prostate-specific membrane antigen small-molecule radiotracers using a solid-phase 99mTc preloading strategy.
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pubmed:affiliation |
Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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