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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-6-26
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pubmed:abstractText |
To construct recombinant lentiviral vectors for gene delivery of the glial cell line-derived neurotrophic factor (GDNF), and evaluate the neuroprotective effect of GDNF on lactacystin-damaged PC12 cells by transfecting it into bone marrow stromal cells (BMSCs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcysteine,
http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Conditioned,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Recombinant,
http://linkedlifedata.com/resource/pubmed/chemical/Glial Cell Line-Derived...,
http://linkedlifedata.com/resource/pubmed/chemical/Neuroprotective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Protease Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/lactacystin
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1673-7067
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-74
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pubmed:meshHeading |
pubmed-meshheading:17592528-Acetylcysteine,
pubmed-meshheading:17592528-Animals,
pubmed-meshheading:17592528-Bone Marrow Cells,
pubmed-meshheading:17592528-Cells, Cultured,
pubmed-meshheading:17592528-Culture Media, Conditioned,
pubmed-meshheading:17592528-DNA, Recombinant,
pubmed-meshheading:17592528-Gene Therapy,
pubmed-meshheading:17592528-Genetic Vectors,
pubmed-meshheading:17592528-Glial Cell Line-Derived Neurotrophic Factor,
pubmed-meshheading:17592528-Lentivirus,
pubmed-meshheading:17592528-Neurons,
pubmed-meshheading:17592528-Neuroprotective Agents,
pubmed-meshheading:17592528-PC12 Cells,
pubmed-meshheading:17592528-Plasmids,
pubmed-meshheading:17592528-Protease Inhibitors,
pubmed-meshheading:17592528-RNA, Messenger,
pubmed-meshheading:17592528-Rats,
pubmed-meshheading:17592528-Rats, Sprague-Dawley,
pubmed-meshheading:17592528-Stromal Cells,
pubmed-meshheading:17592528-Transduction, Genetic
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pubmed:year |
2007
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pubmed:articleTitle |
Overexpression of lentivirus-mediated glial cell line-derived neurotrophic factor in bone marrow stromal cells and its neuroprotection for the PC12 cells damaged by lactacystin.
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pubmed:affiliation |
Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China. wangjian336@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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