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rdf:type |
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lifeskim:mentions |
umls-concept:C0021081,
umls-concept:C0023911,
umls-concept:C0030705,
umls-concept:C0085149,
umls-concept:C0085295,
umls-concept:C0152035,
umls-concept:C0332293,
umls-concept:C0376622,
umls-concept:C0535996,
umls-concept:C1456820,
umls-concept:C1882417
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pubmed:issue |
1-2
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pubmed:dateCreated |
2007-7-9
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pubmed:abstractText |
Cytokine production in the host immune response after transplantation may contribute to the variable CYP3A-dependent drug disposition. We investigated the effect of TNF-alpha, IL-10, CYP3A5 and ABCB1 polymorphisms on immunosuppressant tacrolimus pharmacokinetics in liver transplant patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ABCB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/Tacrolimus,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
383
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17568575-Adult,
pubmed-meshheading:17568575-Aged,
pubmed-meshheading:17568575-Asian Continental Ancestry Group,
pubmed-meshheading:17568575-Cytochrome P-450 CYP3A,
pubmed-meshheading:17568575-Cytochrome P-450 Enzyme System,
pubmed-meshheading:17568575-Female,
pubmed-meshheading:17568575-Gene Frequency,
pubmed-meshheading:17568575-Humans,
pubmed-meshheading:17568575-Immunosuppressive Agents,
pubmed-meshheading:17568575-Interleukin-10,
pubmed-meshheading:17568575-Liver Transplantation,
pubmed-meshheading:17568575-Male,
pubmed-meshheading:17568575-Middle Aged,
pubmed-meshheading:17568575-P-Glycoprotein,
pubmed-meshheading:17568575-Pharmacogenetics,
pubmed-meshheading:17568575-Pharmacokinetics,
pubmed-meshheading:17568575-Polymorphism, Single Nucleotide,
pubmed-meshheading:17568575-Retrospective Studies,
pubmed-meshheading:17568575-Tacrolimus,
pubmed-meshheading:17568575-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
Polymorphisms of tumor necrosis factor-alpha, interleukin-10, cytochrome P450 3A5 and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus.
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pubmed:affiliation |
Department of Pharmacology, Basic Medical School, Beijing University, Beijing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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