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rdf:type |
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lifeskim:mentions |
umls-concept:C0006434,
umls-concept:C0017262,
umls-concept:C0023516,
umls-concept:C0026473,
umls-concept:C0036983,
umls-concept:C0086418,
umls-concept:C0175668,
umls-concept:C0185117,
umls-concept:C0205082,
umls-concept:C0205216,
umls-concept:C0439793,
umls-concept:C1707520,
umls-concept:C2911684
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|
pubmed:issue |
8
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pubmed:dateCreated |
2007-8-16
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pubmed:abstractText |
Severe thermal injury causes immune dysfunctions involving both pro- and anti-inflammatory mechanisms. It subsequently leads to a state of immune deficiency that shares some similarities with sepsis-induced immunosuppression. A hallmark of the latter is established by decreased monocyte human leukocyte antigen-DR (mHLA-DR) measurements. The main objective of the current study was to characterize the appearance and the duration of low mHLA-DR expression after severe burn as well as to determine its correlation with mortality and septic complications.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0090-3493
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1910-7
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pubmed:meshHeading |
pubmed-meshheading:17568330-Adolescent,
pubmed-meshheading:17568330-Adult,
pubmed-meshheading:17568330-Aged,
pubmed-meshheading:17568330-Biological Markers,
pubmed-meshheading:17568330-Burns,
pubmed-meshheading:17568330-Female,
pubmed-meshheading:17568330-HLA-DR Antigens,
pubmed-meshheading:17568330-Humans,
pubmed-meshheading:17568330-Immunocompromised Host,
pubmed-meshheading:17568330-Interleukin-10,
pubmed-meshheading:17568330-Interleukin-6,
pubmed-meshheading:17568330-Male,
pubmed-meshheading:17568330-Middle Aged,
pubmed-meshheading:17568330-Monocytes,
pubmed-meshheading:17568330-Shock, Septic,
pubmed-meshheading:17568330-Survival Analysis,
pubmed-meshheading:17568330-Trauma Severity Indices,
pubmed-meshheading:17568330-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
Decreased monocyte human leukocyte antigen-DR expression after severe burn injury: Correlation with severity and secondary septic shock.
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pubmed:affiliation |
Hospices Civils de Lyon, Hôpital Neurologique, Laboratoire d'Immunologie, Lyon, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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