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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1992-2-3
|
| pubmed:abstractText |
To distinguish high-risk patients prior to implantation of a Jarvik-7 artificial heart as a bridge to transplantation, our 37 attempts were reviewed retrospectively. Arbitrary scores of 1 to 4 were given for nine preoperative factors on the basis of results obtained by uni- and multivariate analyses between successful cases and failed attempts; transplant rejection (scored 4: S4) or postoperative heart failure (S3) as the indication, recipient height less than 175 cm (S3), body surface area less than 1.8 m2 (S3), hyperbilirubinemia greater than 24 microM/l (S2), preoperative renal failure requiring dialysis (S2), weight less than 60 kg (S2), and age greater than 40 years (S1). All except one of the 16 patients with successful bridge had a total score of less than 4, with an average score of 1.3 in contrast to 6.6 in the 21 failed cases (p less than 0.001). Among the 17 patients who scored less than 4, 15 received transplants (specificity 90%), while only one qualified for transplantation among 20 patients who scored 4 or more (sensitivity 94%). The two unpredicted failures resulted from mediastinitis and pulmonary infarction, both attributable to postoperative management. Multiple preoperative factors in combination could have successfully predicted the outcome of mechanical support in our experience. These results underscore the importance of patient selection to achieve successful and effective use of the Jarvik-7 as a bridge to heart transplantation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1010-7940
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
509-14
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1756042-Adolescent,
pubmed-meshheading:1756042-Adult,
pubmed-meshheading:1756042-Female,
pubmed-meshheading:1756042-Heart, Artificial,
pubmed-meshheading:1756042-Heart Transplantation,
pubmed-meshheading:1756042-Humans,
pubmed-meshheading:1756042-Male,
pubmed-meshheading:1756042-Middle Aged,
pubmed-meshheading:1756042-Multivariate Analysis,
pubmed-meshheading:1756042-Preoperative Care,
pubmed-meshheading:1756042-Regression Analysis,
pubmed-meshheading:1756042-Risk Factors,
pubmed-meshheading:1756042-Treatment Outcome
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Preoperative risk analysis in patients receiving Jarvik-7 artificial heart as a bridge to transplantation.
|
| pubmed:affiliation |
Department of Cardiovascular Surgery, Hôpital de la Pitié, Paris, France.
|
| pubmed:publicationType |
Journal Article
|