Linked Life Data

17522951

Source:http://linkedlifedata.com/resource/pubmed/id/17522951

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-10-22
pubmed:abstractText
We determine experimentally the accuracy of pulsed photothermal radiometric (PPTR) temperature depth profiling in water-based samples. We use custom tissue phantoms composed of agar gel layers separated by very thin absorbing layers. Two configurations of the acquisition system are compared, one using the customary spectral band of the InSb radiation detector (3.0-5.5 microm) and the other with a spectrally narrowed acquisition band (4.5-5.5 microm). The laser-induced temperature depth profiles are reconstructed from measured radiometric signals using a custom minimization algorithm. The results correlate very well with phantom geometry as determined by optical coherence tomography (OCT) and histology in all evaluated samples. Determination of the absorbing layer depth shows good repeatability with spatial resolution decreasing with depth. Spectral filtering improves the accuracy and resolution, especially for shallow absorption layers (~120 microm) and more complex structures (e.g., with two absorbing layers). The average full width at half maximum (FWHM) of the temperature peaks equals 23% of the layer depth.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0268-8921
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
279-84
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Pulsed photothermal temperature profiling of agar tissue phantoms.
pubmed:affiliation
Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia. matija.milanic@ijs.si
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural