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rdf:type |
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lifeskim:mentions |
umls-concept:C0334227,
umls-concept:C0376358,
umls-concept:C0682972,
umls-concept:C0752312,
umls-concept:C1370600,
umls-concept:C1514485,
umls-concept:C1515844,
umls-concept:C1515877,
umls-concept:C1879547,
umls-concept:C1976850,
umls-concept:C2677316
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pubmed:issue |
1-2
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|
pubmed:dateCreated |
2007-7-9
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pubmed:abstractText |
Hypertriglyceridemia was recently shown to be a risk factor for prostate cancer; however, there are only a few reports about the relationship between prostate cancer and TG (triglycerides) rich lipoproteins. Remnant lipoproteins (RLP) are TG-rich lipoproteins, which are produced by the hydrolysis of very low density lipoproteins and chylomicrons. We examined the direct effect of RLP on the proliferation and signal transduction of prostate cancer cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-8981
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
383
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
78-84
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17512923-Cell Line, Tumor,
pubmed-meshheading:17512923-Cell Proliferation,
pubmed-meshheading:17512923-Chylomicrons,
pubmed-meshheading:17512923-Humans,
pubmed-meshheading:17512923-Hypertriglyceridemia,
pubmed-meshheading:17512923-Lipoproteins,
pubmed-meshheading:17512923-Lipoproteins, VLDL,
pubmed-meshheading:17512923-Male,
pubmed-meshheading:17512923-Mitogen-Activated Protein Kinases,
pubmed-meshheading:17512923-Phosphorylation,
pubmed-meshheading:17512923-Prostatic Neoplasms,
pubmed-meshheading:17512923-Protein Kinase C,
pubmed-meshheading:17512923-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:17512923-Receptors, G-Protein-Coupled,
pubmed-meshheading:17512923-Signal Transduction
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pubmed:year |
2007
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pubmed:articleTitle |
Remnant lipoproteins stimulate proliferation and activate MAPK and Akt signaling pathways via G protein-coupled receptor in PC-3 prostate cancer cells.
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pubmed:affiliation |
Department of Urology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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