Linked Life Data

17507619

Source:http://linkedlifedata.com/resource/pubmed/id/17507619

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-5-17
pubmed:abstractText
Increased mammographic breast density is considered an intermediate marker of breast cancer risk. Physical activity is believed to reduce breast cancer risk; however, its effect on breast density is not well understood. We studied the association between recreational physical activity and mammographic characteristics of the breast among a population of premenopausal and postmenopausal women enrolled as controls (n = 728) in a case-control study of mammographic breast density and breast cancer. Women were enrolled shortly after obtaining their regular screening mammograms, and participants reported their current and lifetime recreational physical activity history using a self-administered, reliable questionnaire at study enrollment. Linear regression was used to determine associations between physical activity variables and the dense breast area, non-dense area, total breast area, and percent density. Age-adjusted analyses revealed significant inverse associations between physical activity variables and the non-dense area and total area and positive associations with percent breast density. These associations were attenuated and nonsignificant after adjustment for body mass index (BMI). Adjustment for additional factors did not substantially change the results. Physical activity was not associated with the dense breast area before or after adjustment for BMI. Self-reported recreational physical activity was not significantly associated with the mammographic characteristics of the breast after adjustment for BMI in this population. These results suggest that the mechanism by which physical activity reduces breast cancer risk may not involve breast density.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1055-9965
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
934-42
pubmed:dateRevised
2007-12-3
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Recreational physical activity and mammographic breast density characteristics.
pubmed:affiliation
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Suite 510, 3520 Fifth Avenue, Pittsburgh, PA 15213, USA. kwr2@pitt.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural