|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2007-5-30
|
|
pubmed:abstractText |
(18)F-Labeled small synthetic peptides have emerged as attractive probes for imaging various molecular targets with PET. The alpha-melanocyte-stimulating hormone (alpha-MSH) receptor (melanocortin type 1 receptor [MC1R]) is overexpressed in most murine and human melanomas. It is a promising molecular target for diagnosis and therapy of melanomas. However, (18)F compounds have not been successfully developed for imaging the MC1R.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0161-5505
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
48
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
987-94
|
|
pubmed:dateRevised |
2007-12-3
|
|
pubmed:meshHeading |
pubmed-meshheading:17504880-Animals,
pubmed-meshheading:17504880-Cell Line, Tumor,
pubmed-meshheading:17504880-Female,
pubmed-meshheading:17504880-Fluorine Radioisotopes,
pubmed-meshheading:17504880-Melanoma, Experimental,
pubmed-meshheading:17504880-Mice,
pubmed-meshheading:17504880-Mice, Inbred C57BL,
pubmed-meshheading:17504880-Neoplasm Transplantation,
pubmed-meshheading:17504880-Peptide Fragments,
pubmed-meshheading:17504880-Positron-Emission Tomography,
pubmed-meshheading:17504880-Radiopharmaceuticals,
pubmed-meshheading:17504880-Receptor, Melanocortin, Type 1,
pubmed-meshheading:17504880-Tissue Distribution,
pubmed-meshheading:17504880-Transplantation, Heterologous,
pubmed-meshheading:17504880-alpha-MSH
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Small-animal PET of melanocortin 1 receptor expression using a 18F-labeled alpha-melanocyte-stimulating hormone analog.
|
|
pubmed:affiliation |
Molecular Imaging Program at Stanford, Stanford University, Stanford, California 94305, USA. zcheng@stanford.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
