Source:http://linkedlifedata.com/resource/pubmed/id/17477700
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-5-4
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pubmed:abstractText |
We present methods for visualizing the dynamic response of biological samples to laser-induced heating. Our approach utilizes optical frequency-domain imaging to detect, spatially localize, and monitor unique dynamic signatures that arise within zones of active tissue denaturation. Since this information is precisely registered with high-resolution ( approximately 10 microm) cross sectional images, regions of thermally destroyed tissue can be mapped in relation to pre-existing morphology. Using porcine esophageal specimens ex vivo, we demonstrate that the extent and evolution of laser thermal damage can be assessed in real time.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1083-3668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
020501
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17477700-Animals,
pubmed-meshheading:17477700-Computer Systems,
pubmed-meshheading:17477700-Esophagus,
pubmed-meshheading:17477700-Hyperthermia, Induced,
pubmed-meshheading:17477700-Image Interpretation, Computer-Assisted,
pubmed-meshheading:17477700-Laser Coagulation,
pubmed-meshheading:17477700-Microscopy,
pubmed-meshheading:17477700-Surgery, Computer-Assisted,
pubmed-meshheading:17477700-Swine,
pubmed-meshheading:17477700-Tomography, Optical Coherence
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pubmed:articleTitle |
Real-time microscopic visualization of tissue response to laser thermal therapy.
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pubmed:affiliation |
Harvard Medical School and Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, BAR 703, Boston, Massachusetts 02114, USA. bvakoc@partners.org
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Research Support, N.I.H., Extramural
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