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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19
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pubmed:dateCreated |
2007-5-15
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pubmed:abstractText |
The inability of aspirin (acetylsalicylic acid [ASA]) to adequately suppress platelet function is associated with future risk of myocardial infarction, stroke, and cardiovascular death. Genetic variation is a proposed but unproved mechanism for insufficient ASA responsiveness.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/11-dehydro-2,3-dinor-thromboxane B2,
http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Aspirin,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Thromboxane B2,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Thromboglobulin
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BeckerDiane MDM,
pubmed-author:BeckerLewis CLC,
pubmed-author:BrayPaul FPF,
pubmed-author:FallinM DanieleMD,
pubmed-author:FaradayNauderN,
pubmed-author:Herrera-GaleanoJ EnriqueJE,
pubmed-author:MathiasRasikaR,
pubmed-author:MoyTaryn FTF,
pubmed-author:VaidyaDhananjayD,
pubmed-author:WilsonAlexander FAF,
pubmed-author:YanekLisa RLR
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2490-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17470694-Adult,
pubmed-meshheading:17470694-African Americans,
pubmed-meshheading:17470694-Arachidonic Acid,
pubmed-meshheading:17470694-Aspirin,
pubmed-meshheading:17470694-Blood Platelets,
pubmed-meshheading:17470694-Cardiovascular Diseases,
pubmed-meshheading:17470694-Coronary Disease,
pubmed-meshheading:17470694-Cyclooxygenase 1,
pubmed-meshheading:17470694-Cyclooxygenase Inhibitors,
pubmed-meshheading:17470694-Drug Resistance,
pubmed-meshheading:17470694-Dyslipidemias,
pubmed-meshheading:17470694-European Continental Ancestry Group,
pubmed-meshheading:17470694-Female,
pubmed-meshheading:17470694-Genetic Heterogeneity,
pubmed-meshheading:17470694-Genetic Predisposition to Disease,
pubmed-meshheading:17470694-Genetic Variation,
pubmed-meshheading:17470694-Humans,
pubmed-meshheading:17470694-Hyperglycemia,
pubmed-meshheading:17470694-Hypertension,
pubmed-meshheading:17470694-Male,
pubmed-meshheading:17470694-Membrane Proteins,
pubmed-meshheading:17470694-Middle Aged,
pubmed-meshheading:17470694-Phenotype,
pubmed-meshheading:17470694-Platelet Activation,
pubmed-meshheading:17470694-Platelet Aggregation,
pubmed-meshheading:17470694-Platelet Aggregation Inhibitors,
pubmed-meshheading:17470694-Prospective Studies,
pubmed-meshheading:17470694-Risk Factors,
pubmed-meshheading:17470694-Sex Characteristics,
pubmed-meshheading:17470694-Smoking,
pubmed-meshheading:17470694-Thrombophilia,
pubmed-meshheading:17470694-Thrombosis,
pubmed-meshheading:17470694-Thromboxane B2,
pubmed-meshheading:17470694-beta-Thromboglobulin
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pubmed:year |
2007
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pubmed:articleTitle |
Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.
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pubmed:affiliation |
Department of Anesthesiology/Critical Care Medicine, Division of Cardiac Surgical Intensive Care, Johns Hopkins Medical Institutions, Baltimore, MD, USA. nfaraday@jhmi.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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