17457195

Source:http://linkedlifedata.com/resource/pubmed/id/17457195

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0010749, umls-concept:C0086418, umls-concept:C0127400, umls-concept:C0162638, umls-concept:C0752312, umls-concept:C1182610, umls-concept:C1370600, umls-concept:C1704259, umls-concept:C1705987
pubmed:issue	4
pubmed:dateCreated	2007-4-25
pubmed:abstractText	To study whether hyperosmolarity induces apoptosis in human corneal epithelial cells through cytochrome c-mediated death pathways and by activation of mitogen-activated protein kinases (MAPKs).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/EY014553, http://linkedlifedata.com/resource/pubmed/grant/EY11915
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8216186
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/4-(4-fluorophenyl)-2-(4-hydroxypheny..., http://linkedlifedata.com/resource/pubmed/chemical/BAX protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 1, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3, http://linkedlifedata.com/resource/pubmed/chemical/Cytochromes c, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Flavonoids, http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/PD 98059, http://linkedlifedata.com/resource/pubmed/chemical/Pyridines, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Saline Solution, Hypertonic, http://linkedlifedata.com/resource/pubmed/chemical/bcl-2-Associated X Protein
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0277-3740
pubmed:author	pubmed-author:LiDe-QuanDQ, pubmed-author:LuoLihuiL, pubmed-author:PflugfelderStephen CSC
pubmed:issnType	Print
pubmed:volume	26
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	452-60
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17457195-Apoptosis, pubmed-meshheading:17457195-Blotting, Western, pubmed-meshheading:17457195-Caspase 1, pubmed-meshheading:17457195-Caspase 3, pubmed-meshheading:17457195-Cell Culture Techniques, pubmed-meshheading:17457195-Cytochromes c, pubmed-meshheading:17457195-Enzyme Inhibitors, pubmed-meshheading:17457195-Epithelium, Corneal, pubmed-meshheading:17457195-Flavonoids, pubmed-meshheading:17457195-Fluorescent Antibody Technique, Indirect, pubmed-meshheading:17457195-Humans, pubmed-meshheading:17457195-Imidazoles, pubmed-meshheading:17457195-Infant, pubmed-meshheading:17457195-MAP Kinase Signaling System, pubmed-meshheading:17457195-Microscopy, Confocal, pubmed-meshheading:17457195-Mitogen-Activated Protein Kinases, pubmed-meshheading:17457195-Osmolar Concentration, pubmed-meshheading:17457195-Pyridines, pubmed-meshheading:17457195-RNA, Messenger, pubmed-meshheading:17457195-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:17457195-Saline Solution, Hypertonic, pubmed-meshheading:17457195-bcl-2-Associated X Protein
pubmed:year	2007
pubmed:articleTitle	Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways.
pubmed:affiliation	Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX 77030, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural