|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0017710,
umls-concept:C0024429,
umls-concept:C0087111,
umls-concept:C0302350,
umls-concept:C0312359,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1334507,
umls-concept:C1456820,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1882417,
umls-concept:C2911692
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|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2007-10-15
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|
pubmed:abstractText |
Macrophage migration inhibitory factor (MIF) is an inflammatory mediator associated with RA severity. In various diseases, MIF polymorphisms are associated with clinical response glucocorticoid (GC) treatment. It is unclear whether MIF polymorphisms determine GC response in rheumatoid arthritis (RA) and to other RA treatments. Therefore, the question of whether two functional variants in MIF are associated with the response to tumour necrosis factor (TNF)alpha-neutralising and GC treatments in RA was investigated.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0003-4967
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
66
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1525-30
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|
pubmed:dateRevised |
2010-11-2
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|
pubmed:meshHeading |
pubmed-meshheading:17456524-Adult,
pubmed-meshheading:17456524-Aged,
pubmed-meshheading:17456524-Antibodies, Monoclonal,
pubmed-meshheading:17456524-Antirheumatic Agents,
pubmed-meshheading:17456524-Arthritis, Rheumatoid,
pubmed-meshheading:17456524-Cohort Studies,
pubmed-meshheading:17456524-Female,
pubmed-meshheading:17456524-Glucocorticoids,
pubmed-meshheading:17456524-Humans,
pubmed-meshheading:17456524-Macrophage Migration-Inhibitory Factors,
pubmed-meshheading:17456524-Male,
pubmed-meshheading:17456524-Middle Aged,
pubmed-meshheading:17456524-Phenotype,
pubmed-meshheading:17456524-Polymorphism, Genetic,
pubmed-meshheading:17456524-Prognosis,
pubmed-meshheading:17456524-Registries,
pubmed-meshheading:17456524-Severity of Illness Index,
pubmed-meshheading:17456524-Treatment Outcome,
pubmed-meshheading:17456524-Tumor Necrosis Factor-alpha
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Macrophage migration inhibitory factor polymorphisms do not predict therapeutic response to glucocorticoids or to tumour necrosis factor alpha-neutralising treatments in rheumatoid arthritis.
|
|
pubmed:affiliation |
Department of Rheumatology, Experimental Rheumatology and Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, PO 6525 GA, Nijmegen, The Netherlands. t.radstake@reuma.umcn.nl
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|
pubmed:publicationType |
Journal Article,
Multicenter Study
|
