Linked Life Data

17357587

Source:http://linkedlifedata.com/resource/pubmed/id/17357587

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-3-15
pubmed:abstractText
A series of new trimethoprim [5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,4- diamine] analogues were prepared by condensation of adamantane-1-carbaldehyde with 3-methoxypropionitrile, followed by reaction of resulting mixture of 2-adamantan-1-ylmethyl-3-methoxy-acrylonitrile and 3-adamantan-1-yl-2-methoxymethyl-acrylonitrile with guanidine, acetamidine and thiourea, respectively. The activity of compounds obtained and sulfamethoxazole, alone and in combination, against several bacterial strains, as well as fungi was investigated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6837
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
374-7
pubmed:meshHeading
pubmed:articleTitle
Synthesis and antibacterial activity of 5-adamantan-1-yl-methyl analogues of trimethoprim.
pubmed:affiliation
Warsaw University of Technology, Faculty of Chemistry, 75 Koszykowa St., 00-662 Warsaw.
pubmed:publicationType
Journal Article