| pubmed-article:17352658 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C1565860 | lld:lifeskim |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C1705323 | lld:lifeskim |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C0262950 | lld:lifeskim |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:17352658 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:17352658 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:17352658 | pubmed:dateCreated | 2007-5-16 | lld:pubmed |
| pubmed-article:17352658 | pubmed:abstractText | Chronic metabolic acidosis induces net Ca efflux from bone; this osteoclastic bone resorption is mediated by increased osteoblastic prostaglandin synthesis. Cyclooxygenase, the rate-limiting enzyme in prostaglandin synthesis, is present in both constitutive (COX-1) and inducible (COX-2) forms. We report here that acidosis increases both osteoblastic RNA and protein levels for COX-2 and that genetic deficiency or pharmacologic inhibition of COX-2 significantly reduces acid-induced Ca efflux from bone. | lld:pubmed |
| pubmed-article:17352658 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17352658 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17352658 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17352658 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17352658 | pubmed:issn | 0884-0431 | lld:pubmed |
| pubmed-article:17352658 | pubmed:author | pubmed-author:BushinskyDavi... | lld:pubmed |
| pubmed-article:17352658 | pubmed:author | pubmed-author:KriegerNancy... | lld:pubmed |
| pubmed-article:17352658 | pubmed:author | pubmed-author:FrickKevin... | lld:pubmed |
| pubmed-article:17352658 | pubmed:author | pubmed-author:LaPlante... | lld:pubmed |
| pubmed-article:17352658 | pubmed:author | pubmed-author:MichalenkaAnn... | lld:pubmed |
| pubmed-article:17352658 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17352658 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:17352658 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17352658 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17352658 | pubmed:pagination | 907-17 | lld:pubmed |
| pubmed-article:17352658 | pubmed:dateRevised | 2007-12-3 | lld:pubmed |
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| pubmed-article:17352658 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17352658 | pubmed:articleTitle | Regulation of COX-2 mediates acid-induced bone calcium efflux in vitro. | lld:pubmed |
| pubmed-article:17352658 | pubmed:affiliation | Department of Medicine, Division of Nephrology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA. | lld:pubmed |
| pubmed-article:17352658 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17352658 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:17352658 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17352658 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17352658 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17352658 | lld:pubmed |
