Source:http://linkedlifedata.com/resource/pubmed/id/17329019
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-7-2
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pubmed:abstractText |
Phosphodiesterase 5 (PDE5) inhibitors improve smooth muscle relaxation and therefore are considered for pharmacotherapy of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Cyclic guanosine monophosphate (cGMP)-dependent protein kinase-1 (cGKI) has been identified as one of the downstream targets for cGMP. The aim of the present study was to evaluate, by means of immunohistochemistry and Western blot analysis, the expression and localization of cGKI isoforms in relation to smooth muscle alpha-actin and cGMP in the human prostate.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0302-2838
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
495-501
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17329019-Actins,
pubmed-meshheading:17329019-Aged,
pubmed-meshheading:17329019-Blotting, Western,
pubmed-meshheading:17329019-Cyclic GMP,
pubmed-meshheading:17329019-Cyclic GMP-Dependent Protein Kinases,
pubmed-meshheading:17329019-Humans,
pubmed-meshheading:17329019-Immunohistochemistry,
pubmed-meshheading:17329019-Male,
pubmed-meshheading:17329019-Middle Aged,
pubmed-meshheading:17329019-Prostate,
pubmed-meshheading:17329019-Prostatic Neoplasms
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pubmed:year |
2007
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pubmed:articleTitle |
Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue.
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pubmed:affiliation |
Hannover Medical School, Department of Urology, 30625 Hannover, Germany. waldkirch.eginhard@mh-hannover.de
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pubmed:publicationType |
Journal Article
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