|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012923,
umls-concept:C0021079,
umls-concept:C0021080,
umls-concept:C0024128,
umls-concept:C0086589,
umls-concept:C0150369,
umls-concept:C0181090,
umls-concept:C0205087,
umls-concept:C0302614,
umls-concept:C0392756,
umls-concept:C0542560,
umls-concept:C1550025,
umls-concept:C1706050,
umls-concept:C2346689
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2007-2-23
|
|
pubmed:abstractText |
Posttransplant lymphoproliferative disease (PTLD) is a serious complication after lung transplantation and its relation with Epstein-Barr virus (EBV) is well recognized. It has been postulated that preemptive reduction of immunosuppression guided by EBV-DNA load may lead to a significantly lower incidence of PTLD, because of the reconstitution of T-cell control. In this report, we describe the feasibility of this approach in terms of safety with regard to the risk of acute as well as chronic allograft rejection in 75 lung transplant recipients transplanted between 1990 and 2001 and followed for this study from June 1, 2001 until January 1, 2006.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0041-1337
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
27
|
|
pubmed:volume |
83
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
433-8
|
|
pubmed:meshHeading |
pubmed-meshheading:17318076-Acute Disease,
pubmed-meshheading:17318076-Adult,
pubmed-meshheading:17318076-Aged,
pubmed-meshheading:17318076-Biological Markers,
pubmed-meshheading:17318076-Bronchiolitis Obliterans,
pubmed-meshheading:17318076-Clinical Protocols,
pubmed-meshheading:17318076-DNA, Viral,
pubmed-meshheading:17318076-Disease Progression,
pubmed-meshheading:17318076-Epstein-Barr Virus Infections,
pubmed-meshheading:17318076-Female,
pubmed-meshheading:17318076-Graft Rejection,
pubmed-meshheading:17318076-Herpesvirus 4, Human,
pubmed-meshheading:17318076-Humans,
pubmed-meshheading:17318076-Immunosuppressive Agents,
pubmed-meshheading:17318076-Lung Transplantation,
pubmed-meshheading:17318076-Lymphoproliferative Disorders,
pubmed-meshheading:17318076-Male,
pubmed-meshheading:17318076-Middle Aged,
pubmed-meshheading:17318076-Risk Factors,
pubmed-meshheading:17318076-Survival Rate,
pubmed-meshheading:17318076-Time Factors
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Epstein-Barr virus-DNA load monitoring late after lung transplantation: a surrogate marker of the degree of immunosuppression and a safe guide to reduce immunosuppression.
|
|
pubmed:affiliation |
Department of Hematology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.
|
|
pubmed:publicationType |
Journal Article
|
