Linked Life Data

17181062

Source:http://linkedlifedata.com/resource/pubmed/id/17181062

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-12-21
pubmed:abstractText
After single and repeated peroral administration of bemitil to rats this drug was found in the liver, brain, kidneys, spleen, heart, skeletal muscles, lungs, adipose tissue, and testicles. After single treatment accumulation of bemitil was most pronounced in the liver. After repeated treatment the decrease in bemitil concentration in the liver was probably associated with increased elimination of the drug from liver tissue due to intensification of its biotransformation. We conclude that bemitil can accumulate in the blood, but not in tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0007-4888
pubmed:author
pubmed:issnType
Print
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
596-8
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Distribution of bemitil in organs and tissues of rats after single or repeated administration.
pubmed:affiliation
All-Russia Research Center on Safety of Biologically Active Substances, Staraya Kupavna, Moscow region. nauka@materiamedica.ru
pubmed:publicationType
Journal Article, Comparative Study