|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0014406,
umls-concept:C0017262,
umls-concept:C0026845,
umls-concept:C0038250,
umls-concept:C0079259,
umls-concept:C0162371,
umls-concept:C0332157,
umls-concept:C1171362,
umls-concept:C1515655,
umls-concept:C1515670,
umls-concept:C1533691,
umls-concept:C1704336
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2007-3-16
|
|
pubmed:abstractText |
Duchenne muscular dystrophy is a disease characterized by progressive and irreversible muscle degeneration for which there is no therapy. HUCB (human umbilical cord blood) has been considered as an important source of haematopoietic and mesenchymal stem cells, each having been shown to differentiate into distinct cell types. However, it remains unclear if these cells are able to differentiate into muscle cells.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0248-4900
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
99
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
185-96
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|
pubmed:dateRevised |
2008-11-21
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|
pubmed:meshHeading |
pubmed-meshheading:17166095-Animals,
pubmed-meshheading:17166095-Biological Markers,
pubmed-meshheading:17166095-Cell Culture Techniques,
pubmed-meshheading:17166095-Cell Differentiation,
pubmed-meshheading:17166095-Cell Fusion,
pubmed-meshheading:17166095-Cells, Cultured,
pubmed-meshheading:17166095-Coculture Techniques,
pubmed-meshheading:17166095-Dystrophin,
pubmed-meshheading:17166095-Fetal Blood,
pubmed-meshheading:17166095-Fluorescent Antibody Technique, Direct,
pubmed-meshheading:17166095-Green Fluorescent Proteins,
pubmed-meshheading:17166095-Humans,
pubmed-meshheading:17166095-Immunohistochemistry,
pubmed-meshheading:17166095-Male,
pubmed-meshheading:17166095-Mice,
pubmed-meshheading:17166095-Mice, Inbred mdx,
pubmed-meshheading:17166095-Muscle, Skeletal,
pubmed-meshheading:17166095-Muscle Fibers, Skeletal,
pubmed-meshheading:17166095-Stem Cell Transplantation,
pubmed-meshheading:17166095-Stem Cells,
pubmed-meshheading:17166095-Time Factors,
pubmed-meshheading:17166095-Transplantation, Heterologous
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Stem cells from umbilical cord blood differentiate into myotubes and express dystrophin in vitro only after exposure to in vivo muscle environment.
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|
pubmed:affiliation |
Human Genome Research Center, Department of Genetics and Evolutionary Biology, University of Sao Paulo, Sao Paulo, SP, Brazil. vanunes@ib.usp.br
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|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
