Source:http://linkedlifedata.com/resource/pubmed/id/17162094
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-12-12
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pubmed:abstractText |
Silodosin (KMD-3213 or [(-)-1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide]) (Kissei Pharmaceutical Co., Ltd., Matsumoto, Japan) is a selective antagonist for alpha-1A and alpha-1L adrenoceptors. Using this tritiated ligand the 2 alpha-1 adrenoceptors were examined in binding studies with intact tissue segments and membrane preparations of human prostate, and compared with functionally identified alpha-1 adrenoceptor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-81
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pubmed:meshHeading | |
pubmed:year |
2007
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pubmed:articleTitle |
Identification of alpha-1L and alpha-1A adrenoceptors in human prostate by tissue segment binding.
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pubmed:affiliation |
Division of Pharmacology, Department of Biochemistry and Bioinformative Sciences, and Division of Urology, Department of Surgery, School of Medicine, University of Fukui, Matsuoka, Fukui, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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