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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-9-27
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pubmed:abstractText |
In order to assess the prevalence of hepatitis C virus (HCV) in polyarteritis nodosa (PN), 38 patients with systemic necrotizing angiitis were retrospectively tested for the presence of anti-HCV antibodies (Ab). Twenty-one patients were hepatitis B virus (HBV) positive, comprising group A, and 17 were HBV negative, comprising group B. Two patients from group A had anti-HCV Ab (2/21: 9.5%). One was treated unsuccessfully with corticosteroids, then with vidarabine and plasma exchanges; HBe/anti-HBe seroconversion was not observed and anti-HCV Ab disappeared 8 months after the onset of PN. The second patient was successfully treated with corticosteroids, then vidarabine and plasma exchanges; he recovered from PN, HBV seroconversion occurred, and the anti HCV Ab remained detectable. These results show that: 1) the prevalence of anti HCV Ab in PN related to HBV is nearly the same (9.5%) as the prevalence of HCV Ab observed in patients with chronic hepatitis related to HBV infection; 2) the course of these two viral infections can be different and the role of HCV as an etiologic factor in PN has not been established.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
253-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1715249-Adult,
pubmed-meshheading:1715249-Aged,
pubmed-meshheading:1715249-Female,
pubmed-meshheading:1715249-Hepacivirus,
pubmed-meshheading:1715249-Hepatitis Antibodies,
pubmed-meshheading:1715249-Hepatitis C,
pubmed-meshheading:1715249-Hepatitis C Antibodies,
pubmed-meshheading:1715249-Humans,
pubmed-meshheading:1715249-Male,
pubmed-meshheading:1715249-Middle Aged,
pubmed-meshheading:1715249-Polyarteritis Nodosa,
pubmed-meshheading:1715249-Prevalence,
pubmed-meshheading:1715249-Retrospective Studies
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pubmed:articleTitle |
Hepatitis C virus in patients with polyarteritis nodosa. Prevalence in 38 patients.
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pubmed:affiliation |
Department of Internal Medicine, University Paris-Nord, Bobigny, France.
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pubmed:publicationType |
Journal Article
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