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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
2006-12-5
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pubmed:abstractText |
We have previously shown the presence of an activated platelet-derived growth factor (PDGF) receptor (PDGFR) B and its ligand PDGFB in a limited number of patients with clinical and radiological responses to imatinib mesylate treatment. This article describes the results of comprehensive molecular/biochemical analyses of the three receptors targeted by the drug (PDGFRB, PDGFRA, and KIT) in a series of 31 chordoma patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:CarboneAntoninoA,
pubmed-author:CasaliPaolo GPG,
pubmed-author:DagradaGian PaoloGP,
pubmed-author:GronchiAlessandroA,
pubmed-author:LagonigroM StefaniaMS,
pubmed-author:MiselliFrancescaF,
pubmed-author:NegriTizianaT,
pubmed-author:PastoreElisaE,
pubmed-author:PerroneFedericaF,
pubmed-author:PierottiMarco AMA,
pubmed-author:PilottiSilvanaS,
pubmed-author:StacchiottiSilviaS,
pubmed-author:StaurengoSamanthaS,
pubmed-author:TamboriniElenaE
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6920-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17145809-Adult,
pubmed-meshheading:17145809-Aged,
pubmed-meshheading:17145809-Blotting, Western,
pubmed-meshheading:17145809-Chordoma,
pubmed-meshheading:17145809-Female,
pubmed-meshheading:17145809-Gene Expression Profiling,
pubmed-meshheading:17145809-Humans,
pubmed-meshheading:17145809-Immunohistochemistry,
pubmed-meshheading:17145809-In Situ Hybridization, Fluorescence,
pubmed-meshheading:17145809-Male,
pubmed-meshheading:17145809-Middle Aged,
pubmed-meshheading:17145809-Phosphorylation,
pubmed-meshheading:17145809-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:17145809-RNA, Messenger,
pubmed-meshheading:17145809-Receptor, Platelet-Derived Growth Factor alpha,
pubmed-meshheading:17145809-Receptor, Platelet-Derived Growth Factor beta,
pubmed-meshheading:17145809-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17145809-Sequence Analysis, DNA
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pubmed:year |
2006
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pubmed:articleTitle |
Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas.
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pubmed:affiliation |
Experimental Molecular Pathology, Department of Pathology, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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