rdf:type |
|
lifeskim:mentions |
umls-concept:C0001483,
umls-concept:C0039508,
umls-concept:C0040300,
umls-concept:C0043240,
umls-concept:C0224848,
umls-concept:C0442335,
umls-concept:C0443286,
umls-concept:C0521026,
umls-concept:C0871261,
umls-concept:C1282749,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1707455,
umls-concept:C2911692
|
pubmed:issue |
10
|
pubmed:dateCreated |
2006-12-5
|
pubmed:abstractText |
Delivery of growth factor genes that may substantially increase the healing rate of injured digital flexor tendons is a new application of gene therapy. Adenoviral, adeno-associated viral (AAV), and liposome-plasmid vectors have been used to deliver genes to tendons, but the tendon reactions to these vectors--particularly in contrast to the healing responses in the injured tendons--were unknown. This study was designed to compare the tissue reactions of the earlier-mentioned vectors in tendons with the healing responses of injured flexor tendons.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0363-5023
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1652-60
|
pubmed:dateRevised |
2009-6-8
|
pubmed:meshHeading |
pubmed-meshheading:17145387-Animals,
pubmed-meshheading:17145387-Cell Proliferation,
pubmed-meshheading:17145387-Cytomegalovirus,
pubmed-meshheading:17145387-Genetic Vectors,
pubmed-meshheading:17145387-Inflammation,
pubmed-meshheading:17145387-Liposomes,
pubmed-meshheading:17145387-Luciferases,
pubmed-meshheading:17145387-Lymphocytes,
pubmed-meshheading:17145387-Neutrophils,
pubmed-meshheading:17145387-Plasmids,
pubmed-meshheading:17145387-Rabbits,
pubmed-meshheading:17145387-Tendon Injuries,
pubmed-meshheading:17145387-Tendons,
pubmed-meshheading:17145387-Wound Healing,
pubmed-meshheading:17145387-beta-Galactosidase
|
pubmed:year |
2006
|
pubmed:articleTitle |
Tissue reactions of adenoviral, adeno-associated viral, and liposome-plasmid vectors in tendons and comparison with early-stage healing responses of injured flexor tendons.
|
pubmed:affiliation |
Hand Surgery Research Center, Department of Hand Surgery, Affiliated Hospital of Nantong University, Nantong, China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|