|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0018270,
umls-concept:C0037081,
umls-concept:C0040223,
umls-concept:C0040508,
umls-concept:C0041370,
umls-concept:C0086860,
umls-concept:C0332162,
umls-concept:C0439611,
umls-concept:C0752046,
umls-concept:C1456820,
umls-concept:C1510411,
umls-concept:C1561656,
umls-concept:C1704829,
umls-concept:C2603343,
umls-concept:C2698872
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2006-12-1
|
|
pubmed:abstractText |
Aseptic loosening resulting from inflammatory response to the implant wear debris is the major cause of late total hip arthroplasty (THA) failure. We examined single nucleotide polymorphisms in genes encoding for three involved cytokines--interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and transforming growth factor-beta1 (TGF-beta1)--as potential predictors of time to onset of aseptic instability.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0949-2658
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
592-600
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:17139467-Adult,
pubmed-meshheading:17139467-Arthroplasty, Replacement, Hip,
pubmed-meshheading:17139467-Female,
pubmed-meshheading:17139467-Genetic Predisposition to Disease,
pubmed-meshheading:17139467-Genotype,
pubmed-meshheading:17139467-Hip Prosthesis,
pubmed-meshheading:17139467-Humans,
pubmed-meshheading:17139467-Interleukin-6,
pubmed-meshheading:17139467-Male,
pubmed-meshheading:17139467-Middle Aged,
pubmed-meshheading:17139467-Polymorphism, Single Nucleotide,
pubmed-meshheading:17139467-Promoter Regions, Genetic,
pubmed-meshheading:17139467-Proportional Hazards Models,
pubmed-meshheading:17139467-Prosthesis Failure,
pubmed-meshheading:17139467-Transforming Growth Factor beta1,
pubmed-meshheading:17139467-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Single nucleotide polymorphisms in the interleukin-6 gene promoter, tumor necrosis factor-alpha gene promoter, and transforming growth factor-beta1 gene signal sequence as predictors of time to onset of aseptic loosening after total hip arthroplasty: preliminary study.
|
|
pubmed:affiliation |
Department of Orthopaedic Surgery, Clinical Hospital Center Zagreb and University School of Medicine, Salata 3, 10000, Zagreb, Croatia.
|
|
pubmed:publicationType |
Journal Article
|
