Source:http://linkedlifedata.com/resource/pubmed/id/17113384
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
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pubmed:dateCreated |
2006-11-20
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pubmed:abstractText |
Hox genes control animal body plans by directing the morphogenesis of segment-specific structures. As transcription factors, HOX proteins achieve this through the activation of downstream target genes. Much research has been devoted to the search for these targets and the characterization of their roles in organogenesis. This has shown that the direct targets of Hox activation are often transcription factors or signaling molecules, which form hierarchical genetic networks directing the morphogenesis of particular organs. Importantly, very few of the direct Hox targets known are "realizator" genes involved directly in the cellular processes of organogenesis.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-9822
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2206-16
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pubmed:dateRevised |
2007-8-13
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pubmed:meshHeading |
pubmed-meshheading:17113384-Animals,
pubmed-meshheading:17113384-Binding Sites,
pubmed-meshheading:17113384-Cell Adhesion,
pubmed-meshheading:17113384-Cell Polarity,
pubmed-meshheading:17113384-Cytoskeleton,
pubmed-meshheading:17113384-DNA Primers,
pubmed-meshheading:17113384-Drosophila,
pubmed-meshheading:17113384-Drosophila Proteins,
pubmed-meshheading:17113384-Gene Expression Regulation, Developmental,
pubmed-meshheading:17113384-Homeodomain Proteins,
pubmed-meshheading:17113384-Larva,
pubmed-meshheading:17113384-Mutagenesis, Site-Directed,
pubmed-meshheading:17113384-Organogenesis,
pubmed-meshheading:17113384-RNA Interference,
pubmed-meshheading:17113384-Signal Transduction
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pubmed:year |
2006
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pubmed:articleTitle |
Coordinated control of cell adhesion, polarity, and cytoskeleton underlies Hox-induced organogenesis in Drosophila.
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pubmed:affiliation |
Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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