Linked Life Data

17103462

Source:http://linkedlifedata.com/resource/pubmed/id/17103462

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-7-2
pubmed:abstractText
Initially, diabetes is commonly associated with an increased glomerular filtration rate (GFR), a potential mechanism involved in the progression of diabetic nephropathy. Several studies have reported reno-protective effects of C-peptide. C-peptide reduces diabetes-induced hyperfiltration, as well as renal hypertrophy and albuminuria. In order to gain further understanding of these effects, it is very important to localize the active sites within the C-peptide molecule. This study was designed to elucidate the effects of the C-peptide fragment EVARQ on kidney function, blood pressure and blood glucose levels in diabetic rats in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1520-7552
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
400-5
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The C-peptide fragment EVARQ reduces glomerular hyperfiltration in streptozotocin-induced diabetic rats.
pubmed:affiliation
Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden. Lina.Nordquist@mcb.uu.se
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't