17049118

Source:http://linkedlifedata.com/resource/pubmed/id/17049118

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0025545, umls-concept:C0045137, umls-concept:C0086597, umls-concept:C1334291, umls-concept:C1367307, umls-concept:C1879547
pubmed:issue	11
pubmed:dateCreated	2006-10-19
pubmed:abstractText	To examine whether isoliquiritigenin (ISL) can attenuate myocardial ischemiareperfusion (MI/R) injury in rats by inducing metallothionein (MT) through activation of janus kinase 2 (JAK 2)/signal transducers and activators of transcription 3 (STAT 3) pathway.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100956087
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Chalcones, http://linkedlifedata.com/resource/pubmed/chemical/Creatine Kinase, http://linkedlifedata.com/resource/pubmed/chemical/Jak2 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinase 2, http://linkedlifedata.com/resource/pubmed/chemical/L-Lactate Dehydrogenase, http://linkedlifedata.com/resource/pubmed/chemical/Metallothionein, http://linkedlifedata.com/resource/pubmed/chemical/Protective Agents, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/Stat3 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Tyrphostins, http://linkedlifedata.com/resource/pubmed/chemical/alpha-cyano-(3,4-dihydroxy)-N-benzyl..., http://linkedlifedata.com/resource/pubmed/chemical/isoliquiritigenin
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1671-4083
pubmed:author	pubmed-author:YangJingJ, pubmed-author:YinHH, pubmed-author:ZILLHH
pubmed:issnType	Print
pubmed:volume	27
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1431-7
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17049118-Animals, pubmed-meshheading:17049118-Chalcones, pubmed-meshheading:17049118-Creatine Kinase, pubmed-meshheading:17049118-Janus Kinase 2, pubmed-meshheading:17049118-L-Lactate Dehydrogenase, pubmed-meshheading:17049118-Male, pubmed-meshheading:17049118-Metallothionein, pubmed-meshheading:17049118-Myocardial Reperfusion Injury, pubmed-meshheading:17049118-Phosphorylation, pubmed-meshheading:17049118-Protective Agents, pubmed-meshheading:17049118-Protein-Tyrosine Kinases, pubmed-meshheading:17049118-RNA, Messenger, pubmed-meshheading:17049118-Rats, pubmed-meshheading:17049118-Rats, Sprague-Dawley, pubmed-meshheading:17049118-STAT3 Transcription Factor, pubmed-meshheading:17049118-Signal Transduction, pubmed-meshheading:17049118-Tyrphostins
pubmed:year	2006
pubmed:articleTitle	Metallothionein mediates cardioprotection of isoliquiritigenin against ischemia-reperfusion through JAK2/STAT3 activation.
pubmed:affiliation	Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China.
pubmed:publicationType	Journal Article