|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2006-9-29
|
|
pubmed:abstractText |
Cyclooxygenase-2 (Cox-2), the inducible key enzyme in the biosynthesis of prostaglandins, appears to play a role in the regulation of progression, invasiveness and angiogenesis of various neoplasms including some glial tumors. Little is known about the role of Cox-2 in angiogenesis and proliferation of ependymomas. We studied Cox-2 expression, Ki-67 labeling index (Ki-67 LI) and microvessel density (MVD) in 30 intracranial ependymomas and analyzed the relationship among these parameters to evaluate their importance in the tumor biology of ependymomas.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0722-5091
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
216-20
|
|
pubmed:meshHeading |
pubmed-meshheading:17007443-Adolescent,
pubmed-meshheading:17007443-Adult,
pubmed-meshheading:17007443-Brain Neoplasms,
pubmed-meshheading:17007443-Cell Proliferation,
pubmed-meshheading:17007443-Child,
pubmed-meshheading:17007443-Child, Preschool,
pubmed-meshheading:17007443-Cyclooxygenase 2,
pubmed-meshheading:17007443-Ependymoma,
pubmed-meshheading:17007443-Female,
pubmed-meshheading:17007443-Humans,
pubmed-meshheading:17007443-Immunohistochemistry,
pubmed-meshheading:17007443-Infant,
pubmed-meshheading:17007443-Ki-67 Antigen,
pubmed-meshheading:17007443-Male,
pubmed-meshheading:17007443-Neovascularization, Pathologic,
pubmed-meshheading:17007443-Tumor Markers, Biological
|
|
pubmed:articleTitle |
Cyclooxygenase-2 (cox-2) expression and angiogenesis in intracranial ependymomas.
|
|
pubmed:affiliation |
Department of Pathology, Gulhane Military Medical Academy, Hacettepe University Faculty of Medicine, Ankara, Turkey. onguruo@yahoo.com
|
|
pubmed:publicationType |
Journal Article
|
