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pubmed-article:16983120pubmed:abstractTextTo improve prognosis in children with acute myeloid leukemia (AML) by randomized comparisons of (1) two short consolidation cycles versus the Berlin-Frankfurt-Muenster (BFM) -type biphasic 6-week consolidation and (2) the prophylactic administration of granulocyte colony-stimulating factor (G-CSF) versus no G-CSF. Further, therapy for standard risk patients was intensified by addition of a second induction, HAM (high-dose cytarabine and mitoxantrone).lld:pubmed
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pubmed-article:16983120pubmed:articleTitleLess toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.lld:pubmed
pubmed-article:16983120pubmed:affiliationDepartment of Hematology/Oncology, University Children's Hospital, Muenster, Germany. ursula@creutzig.delld:pubmed
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